The chances varying from couple to couple and depending on different factors. The probability lies by 20 to 25 per cent, by fertile couples even by 30 per cent. After three treatments a ratio of 40 per cent success is possible. However, it has to be mentioned, that for 50 to 60 per cent of all couples who have the wish to have a child, both methods, the ICSI and the IVF, are not working and they stay childless.